THE ANTIOXIDANT FOR LONGEVITY & CELLULAR DEFENSE
Trans-Resveratrol
Trans-Resveratrol is a powerful polyphenol found in red grapes, berries, and Japanese knotweed—best known for its role in promoting cellular health and longevity. It acts as a potent antioxidant, helping to neutralize free radicals and reduce oxidative stress, one of the key drivers of aging. Trans-Resveratrol has also been shown to activate sirtuins, a group of proteins linked to DNA repair, inflammation control, and healthy aging. With its ability to support cardiovascular health, cognitive function, and cellular resilience, it’s a core ingredient in modern longevity science.
Real-Life Issues Trans-Resveratrol Can Tackle
Backed by Science
At NATURIQ, we don’t just believe in our ingredients—we back them with science. Every formula we create is rooted in evidence, not trends. Trans-Resveratrol is a well-researched antioxidant known for its ability to reduce oxidative stress, support cardiovascular health, and activate sirtuins—proteins linked to DNA repair and longevity.
In this section, you'll find a selection of clinical studies and scientific publications that explain how and why Trans-Resveratrol protects cells, supports brain and heart health, and contributes to healthy aging—so you can feel confident in what you’re putting into your body, and why it matters.
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Author: Berman A.Y., et al.
Published in: Molecules, 2017
Summary: Demonstrates that resveratrol modulates NF-κB and inflammatory cytokines, key drivers of inflammaging. Results suggest long-term supplementation may reduce age-related inflammation and protect against chronic skin damage and degradation. -
Author: Brinke A., Janssens-Böcker C., Kerscher M.
Published in: Journal of Cosmetics, Dermatological Sciences and Applications, 2021
Summary: Clinical study in women aged 40+ showed that a 2% trans-resveratrol emulsion improved skin elasticity by 5.3%, skin density by 10.7%, and reduced roughness and wrinkles. Results support trans-resveratrol’s efficacy in reducing visible signs of aging and improving skin firmness. -
Author: Gęgotek A, Skrzydlewska E
Published in: Advances in Dermatology and Allergology, 2022
Summary: This review highlights resveratrol's protective effects against skin aging by interacting with pathways such as MAPK, FOXO3, and TGF. It enhances collagen synthesis through estrogen receptor activation, reducing wrinkles and improving skin elasticity. Additionally, resveratrol accelerates skin regeneration and healing by activating VEGF, offering potential applications in dermatology and plastic surgery.
WHY WE USE TRANS-RESVERATROL AT NATURIQ
“We use Trans-Resveratrol because it helps protect your cells and extend their vitality. Known as the “longevity molecule,” it works deep within the body to reduce oxidative stress, support heart and brain health, and activate key longevity pathways like sirtuins. Backed by decades of research, it’s one of the most trusted antioxidants in modern wellness—and a cornerstone of our approach to graceful aging and long-term resilience.”
READY TO LIVE TO 100?
Renew
Renew is our science-backed supplement, made in Germany, to support energy, focus, and healthy aging—so you can feel your best at every age.
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Crafted to the highest standards with premium ingredients and strict quality control, because your body deserves nothing less.
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Every capsule is packed with longevity-focused nutrients—like NMN, trans-resveratrol, quercetin, designed to support energy, cellular repair, and graceful aging.
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Backed by science for improved energy, cognitive clarity, and healthy aging—one capsule at a time.
What is Trans-Resveratrol?
Trans-Resveratrol is the most active and bioavailable form of resveratrol, a natural polyphenol found in foods like red grapes, berries, peanuts, and particularly in the skin of red wine grapes. Recognized for its powerful antioxidant and anti-aging properties, Trans-Resveratrol has become one of the most studied compounds in the field of cellular health and longevity. It plays a central role in protecting cells from oxidative damage, reducing inflammation, and promoting the body’s natural repair processes.
One of the key mechanisms behind Trans-Resveratrol’s benefits is its ability to activate sirtuins—especially SIRT1. Sirtuins are a group of proteins that regulate important biological functions such as DNA repair, inflammation control, and cellular aging. Activating these proteins mimics the effects of caloric restriction, a well-documented method for extending lifespan and improving metabolic health in various organisms. Because of this, Trans-Resveratrol is often referred to as a “longevity molecule.”
In addition to activating sirtuins, Trans-Resveratrol is a potent antioxidant that helps neutralize free radicals—unstable molecules that cause oxidative stress and cellular damage. Oxidative stress is a major contributor to aging and is linked to chronic conditions such as cardiovascular disease, neurodegenerative disorders, and insulin resistance. By reducing oxidative stress, Trans-Resveratrol helps preserve mitochondrial function, supports energy production, and promotes healthy aging at the cellular level.Trans-Resveratrol is also widely recognized for its cardiovascular benefits. It has been shown to support healthy blood circulation, improve endothelial function (the health of blood vessel linings), and reduce the oxidation of LDL cholesterol, which is a key factor in the development of plaque in the arteries. These effects contribute to better heart health and may help reduce the risk of age-related cardiovascular issues.
Brain health is another area where Trans-Resveratrol shows promise. Research suggests it may enhance memory, improve focus, and protect against cognitive decline by increasing cerebral blood flow and reducing inflammation in neural tissues. These neuroprotective benefits make it a popular supplement for those looking to maintain mental sharpness as they age. Because it’s the trans-isomer, Trans-Resveratrol is more stable and effective than its counterpart, cis-resveratrol, which is less bioactive and breaks down more easily. However, like many polyphenols, Trans-Resveratrol naturally has low bioavailability. To address this, high-quality supplements often use advanced delivery systems such as liposomal or phytosomal encapsulation, or they pair it with ingredients like piperine to improve absorption.
Trans-Resveratrol is generally well tolerated when used as directed. It is commonly included in anti-aging supplement routines alongside other cellular health nutrients like NMN and CoQ10, where it helps support mitochondrial function and overall vitality. In summary, Trans-Resveratrol is a powerful compound that supports cellular defense, cardiovascular function, cognitive performance, and healthy aging. By working at the molecular level to activate longevity pathways and protect against oxidative stress, it provides comprehensive support for long-term energy, resilience, and wellness.
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